Table 1.
List of 8 SNPs Across the DBH Gene Investigated in this Study
| NCBI SNP reference | dbSNP allele | Public location | Location on gene region | SNP type | Residue change | MAF (HapMap-CHB) |
|---|---|---|---|---|---|---|
| rs1076150 | C/T | chr.9-136498761 | Flanking_5′UTR | Regulatory | – | 0.195 |
| rs1611115 | C/T | chr.9-136500515 | Flanking_5′UTR | Regulatory | NA = > NA | 0.207 |
| rs1108580 | C/T | chr.9-136505114 | Exon 2–intron2 splice junction |
Silent mutation Regulatory |
E [Glu] = > E [Glu] |
0.183 |
| rs2873804 | C/T | chr.9-136505644 | Intron 2 | Regulatory | – | 0.244 |
| rs1548364 | A/G | chr.9-136507742 | Intron 3 | Regulatory | – | – |
| rs2519154 | C/T | chr.9-136512275 | Intron 5 | Regulatory | – | 0.125 |
| rs2073837 | A/G | chr.9-136522928 | Intron 11 | Regulatory | – | – |
| rs129882 | C/T | chr.9-136523669 | UTR 3′ | Regulatory | NA = > NA | 0.366 |
SNP, single nucleotide polymorphism; DBH, dopamine beta hydroxylase; NCBI, National Center for Biotechnology Information; MAF, minor allele frequency; UTR, untranslated region.