Table 4.
Outcomes of the first IVF cycle stratified by age
| Cycle outcome | <25 years N = 163 | 25 to <30 years N = 1691 | P | 30 to <35 years N = 5389 | P a |
|---|---|---|---|---|---|
| Cancelation | 8 (4.9) | 94 (5.6) | 0.73 | 369 (6.9) | 0.33 |
| Oocyte retrieval | 155 (95.1) | 1597 (94.4) | 0.73 | 5020 (93.2) | 0.33 |
| Embryo transferb | 138 (89.0) | 1436 (89.9) | 0.73 | 4519 (90.0) | 0.69 |
| Implantation ratec | 28.2 ± 40.3 | 29.7 ± 40.7 | 0.76 | 29.2 ± 40.5 | 0.84 |
| Outcomes per cycle start | |||||
| Clinical pregnancy | 52 (31.9) | 630 (37.3) | 0.18 | 1947 (36.1) | 0.27 |
| Spontaneous abortion | 3 (1.8) | 61 (3.6) | 0.36 | 225 (4.2) | 0.14 |
| Termination | 0 (0.0) | 2 (0.12) | 1.0 | 11 (0.20) | 1.0 |
| Live birth | 48 (29.5) | 563 (33.3) | 0.32 | 1693 (31.4) | 0.60 |
| Singleton | 30 (62.5) | 377 (67.0) | 0.69d | 1126 (66.5) | 0.70d |
| Twin | 17 (35.4) | 174 (30.9) | 530 (31.3) | ||
| Triplet | 1 (2.1) | 12 (2.1) | 37 (2.2) | ||
| Stillbirth | 0 (0.0) | 1 (0.06) | 1.0 | 9 (0.17) | 1.0 |
| Unknown | 1 (0.61) | 3 (0.18) | 0.31 | 9 (0.17) | 0.26 |
| Outcomes per transfer | |||||
| Clinical pregnancy | 52 (37.7) | 630 (43.9) | 0.16 | 1947 (43.1) | 0.21 |
| Spontaneous abortion | 3 (2.2) | 61 (4.3) | 0.36 | 225 (5.0) | 0.16 |
| Live birth | 48 (34.8) | 563 (39.2) | 0.31 | 1693 (37.5) | 0.52 |
| Singleton | 30 (62.5) | 377 (67.0) | 0.69d | 1126 (66.5) | 0.70d |
| Twin | 17 (35.4) | 174 (30.9) | 530 (31.3) | ||
| Triplet | 1 (2.1) | 12 (2.1) | 37 (2.2) | ||
a P compares women <25 years with women 30 to <35 years
bDenominator is the number of cycles that were not canceled before oocyte retrieval
cThe number of fetal heartbeats divided by the number of transferred embryos among cycles with an embryo transfer
dP is for the 3 × 2 comparison for number of live births, not a pairwise comparison for singletons