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. 2015 Oct 23;6:233. doi: 10.3389/fphar.2015.00233

FIGURE 2.

FIGURE 2

Chemokine and cytokine expression in rats cotreated with LPS and emodin. Rats were treated with emodin (20, 40, or 80 mg/kg, i.g.) or its vehicle (0.5% CMC-Na) and LPS (2.8 mg/kg, i.v.) or its vehicle (0.5% CMC-Na) as described in Figure 1. (A–C) Showed Plasma proinflammatory cytokine levels determined by ELISA for IL-1β, IL-6, and TNF-α respectively. The data were presented as mean ± SD of 10 rats, and statistically significant difference (*P < 0.05, vs emodin groups; ΔP < 0.05, vs LPS group; #P < 0.05 and ##P < 0.01, vs control).