Table 1.
Associations between SUSD4 and clinical parameters
| Factor | Patient | SUSD4+ tumor cells | Patient | SUSD4+ infiltrating cells | |||||
|---|---|---|---|---|---|---|---|---|---|
| No | Yes | P * | 0-15 | 16-100 | P * | ||||
| N | N | ||||||||
| All | 123 | 46 (37) | 77 (63) | 123 | 87 (71) | 36 (29) | |||
| Age at diagnosis | 123 | 0.047 | 123 | 0.006 | |||||
| Median (min, max) | 63 (34, 97) | 67 (35, 91) | 68 (34, 97) | 61 (41, 79) | |||||
| Tumor size, | 123 | 0.066 | 123 | ||||||
| Median mm (min, max) | 23.5 (10, 73) | 21 (7, 145) | 23 (8, 145) | 19.5 (8, 73) | 0.143 | ||||
| NHG | <0.001 | 0.045 | |||||||
| I | N (%) | 15 | 2 (13) | 13 (87) | 17 | 11 (65) | 6 (35) | ||
| II | 58 | 16 (28) | 42 (72) | 56 | 35 (63) | 21 (37) | |||
| III | 50 | 28 (56) | 22 (44) | 50 | 41 (82) | 9 (18) | |||
| Nodal status | 0.027 | 0.853 | |||||||
| 0 | N (%) | 58 | 16 (28) | 42 (72) | 60 | 42 (70) | 18 (30) | ||
| 1-3 | 34 | 14 (41) | 20 (59) | 32 | 23 (72) | 9 (28) | |||
| >4 | 18 | 10 (56) | 8 (44) | 18 | 13 (72) | 5 (28) | |||
| Missing | 13 | 13 | |||||||
| ER status | 0.008 | 0.041 | |||||||
| Negative | N (%) | 18 | 12 (67) | 6 (33) | 17 | 16 (94) | 1 (6) | ||
| Positive | 105 | 34 (32) | 71 (68) | 106 | 71 (67) | 35 (33) | |||
| PR status | 0.117 | 0.295 | |||||||
| Negative N (%) | 40 | 19 (48) | 21 (52) | 40 | 31 (78) | 9 (22) | |||
| Positive | 83 | 27 (32) | 56 (68) | 83 | 56 (68) | 27 (32) | |||
| HER2 | 0.013 | 1.000 | |||||||
| Negative | N (%) | 112 | 38 (34) | 74 (66) | 106 | 77 (73) | 29 (27) | ||
| Positive | 9 | 7 (78) | 2 (22) | 11 | 8 (73) | 3 (27) | |||
| Missing | 2 | 6 | |||||||
| Ki67 | 0.239 | 0.136 | |||||||
| 0-24 % | N (%) | 50 | 17 (34) | 33 (66) | 52 | 34 (65) | 18 (35) | ||
| >25 % | 58 | 27 (47) | 31 (53) | 57 | 45 (79) | 12 (21) | |||
| Missing | 15 | 14 | |||||||
*Mann–Whitney, 2-tailed Exact p-value