. Author manuscript; available in PMC: 2015 Oct 23.

Published in final edited form as: Int J Parasitol. 2008 Dec 24;39(7):747–754. doi: 10.1016/j.ijpara.2008.11.012

Table 2.

Quantitative data for inhibitors used against the Cryptosporidium parvum histone deacetylase 3 protein.

Compound	Class	IC₅₀ in nM	Maximum inhibition
APHA 8	Hydroxamic acid	310 ± 1.2	99%
Apicidin	Cyclic peptide	2100 ± 2.9	63%
Butyrate	Fatty acid	Undetectable	Undetectable
Depudecin	Epoxide	86 ± 2.4	47%
Trichostatin A	Hydroxamic acid	18 ± 1.3	97%
Valproic acid	Fatty acid	Undetectable	Undetectable
Vorinostat	Hydroxamic acid	89 ± 7.9	96%