Table 4.

One- and 2-year rates of PFS, OS, and patients remaining treatment-free (intent-to-treat population)

Outcome	% (95% CI)		Hazard ratio* (95% CI)	P†
	VR-CAP, n = 84	R-CHOP, n = 80
PFS rate‡
1-y	80.0 (69.0-87.5)	82.3 (71.4-89.3)	1.12 (0.57-2.20)	.76
2-y	76.2 (64.2-84.7)	77.1 (65.1-85.4)
OS rate
1-y	91.2 (82.3-95.7)	85.9 (76.0-92.0)	0.89 (0.44-1.81)	.75
2-y	80.1 (69.0-87.5)	79.0 (67.9-86.6)
Treatment-free rate§
1-y	70.6 (59.2-79.4)	78.4 (67.2-86.2)	1.25 (0.69-2.24)	.49
2-y	69.3 (57.8-78.3)	71.8 (59.6-80.9)

^*R-CHOP vs VR-CAP; a HR of <1 indicates an advantage for VR-CAP.

^†Based on the log-rank test (stratified by International Prognostic Index score).

^‡PFS rate by Independent Radiology Review Committee assessment.

^§Patients who had not received subsequent lymphoma therapy or had not died due to progressive disease.