Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
“Double-edged sword” miRNAs in RA. MiR-146a, 155, and 223 have opposite roles in regulating RA pathogenesis. These miRNAs are positively correlated with disease activity through stimulating inflammatory response. On the contrary, they play a role in suppressing joint destruction. The opposite roles of miRNAs give us a lesson to focus more carefully on therapeutic and diagnostic applications of these miRNAs in RA. RA=rheumatoid arthritis.
