Expression of TIPE2 mRNA from peripheral blood mononuclear cells and associations with clinical characteristics in acute-on-chronic hepatitis B liver failure (ACHBLF) patients. (A) TIPE2 mRNA levels in ACHBLF, chronic hepatitis B (CHB), and healthy control (HC) group; (B) TIPE2 mRNA level in survivors and nonsurvivors of patients with ACHBLF (P < 0.001); (C) correlation between TIPE2 mRNA level and ALT level (r = −0.035, P = 0.718); (D) correlation TIPE2 mRNA level and AST level (r = −0.069, P = 0.475); (E) correlation between TIPE2 mRNA level and HBsAg (r = 0.229, P = 0.017); (F) correlation between TIPE2 mRNA level and ALB level (r = −0.191, P = 0.053); (G) correlation between TIPE2 mRNA level and PLT (r = −0.262, P = 0.006); and (H) correlation between TIPE2 mRNA level and MELD score (r = 0.544, P < 0.001). ALB = albumin, ALT = alanine aminotransferase, AST = aspartate aminotransferase, HBsAg = hepatitis B surface antigen, PLT = platelet, TIPE2 = tumor necrosis factor-α-induced protein 8-like 2.