Table 3. Association of ESBL production, presence of integrase genes and MDR with quinolone resistance in E.coli and K.pneumoniae clinical isolates .
Ciprofloxacin resistance a | Nalidixic acid resistance a | ||||
E.coli | K.pneumoniae | E.coli | K.pneumoniae | ||
ESBL producer | 74.2a (26 /35)b | 29 (11/38) | 91.4 (32/35) | 47.3 (18/38) | |
ESBL non producer | 69.2 (9/13) | 18.2 (2/11) | 92.3 (12/13) | 72.8 (8/11) | |
INTEGRON class |
1 | 81.8 (9/11) | 27.2 (6/22) | 100 (11/11) | 50 (11/22) |
2 | 63.6 (7/11) | 20 (1/5) | 81.8 (9/11) | 80 (4/5) | |
1,2 | 100 (9/9) | 25 (1/4) | 100 (9/9) | 50 (2/4) | |
INTEGRON not detected | 58.9 (10/17) | 27.7 (5/18) | 88.2 (15/17) | 50 (9/18) | |
MDR | 69.2 (27/39) | 29.7 (11/37) | 64.8 (37/39) | 54 (20/ 37) | |
Non MDR | 88.8 (8/9) | 16.6 (2/12) | 22 (2/9) | 50 (6/12) |
a Percentage of isolates
b Number of isolates/total number of quinolone resistant isolates