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. 2015 Oct 22;6:542. doi: 10.3389/fimmu.2015.00542

Table 4.

Prime-boost vaccination strategies for viral diseases explored under experimental conditions in finfish.

Disease Prime delivery Boost delivery Fish species Immunogenic protein Antigen Protection Reference
Viral hemorrhagic septicemia Oral Oral Olive flounder Recombinant protein Live High (4)
Infectious pancreatic necrosis Injection Oral Atlantic salmon Inactivated whole virus Inactivated ND* (103)
Infectious salmon anemia virus Injection Oral Atlantic salmon Inactivated whole virus Inactivated ND* (104)
Grouper iridovirus Injection Injection Asian grouper ORF-DNA recombinants Plasmid DNA Low (105)
Spring virus of carp virus Oral Oral Carp Recombinant G-protein Plasmid DNA Moderate (106)
Koi herpesvirus Oral Oral Carp ORF81 protein Plasmid DNA Moderate (106)
Herpesviral hematopoietic necrosis virus Injection Immersion Ryukin gold fish Virus-CyHV-2 Inactivated Moderate (107)

*ND = Not done