TABLE 2.

The frequencies of UGT1A3, UGT1A9, and UGT2B7 genetic variants among HLMs (n = 44)

Gene	Variantsa	Region	Reference	Enzyme Function	Total	wt/wt	wt/mt	mt/mt	Frequencyb (%)
UGT1A3	140T>C	Exon 1	rs6431625	Decrease	44	38	6	0	7
	31T>C	Exon 1	rs3821242	Decrease	44	27	15	2	22
	133C>T	Exon 1	rs45625338	Increase	44	38	5	1	8
UGT1A9	−118T9>T10	Promotor	rs3832043	Increase	44	5	26	13	59
	1399C>T	Intron 1	rs2741049	Increase	44	15	24	5	39
UGT2B7	211G>T	Exon 1	rs12233719	Decrease	44	30	12	2	18
	802C>T	Exon 2	rs7439366	Decrease	44	13	18	13	50

The reference number used was GenBank accession NT_030640.1.

^aPosition is indicated in relation to the start codon ATG of the UGT genes; the A in ATG is +1.

^bAll of the frequencies are within Hardy-Weinberg equation (X², P > 0.05).