TABLE 4.
20-HETE Glucuronidation (pmol/min/mg) | ||||
UGT1A9 Genotype −118T9>T10 1399 C>T | UGT2B7 Genotype 802C>T | n | Mean ± SD | Pa |
T9/T9 C/C | C/C | 0 | 0 | |
C/T | 3 | 346 ± 171 | ||
T/T | 2 | 419 | ||
T9/T10 C/T | C/C | 9 | 786 ± 267 | |
C/T | 8 | 700 ± 110 | <0.0001 | |
T/T | 5 | 536 ± 330 | ||
T10/T10 T/T | C/C | 3 | 1070 ± 247 | |
C/T | 6 | 960 ± 301 | ||
T/T | 3 | 920 ± 199 |
P values were calculated based on one-way ANOVA.