Figure 1. Thymectomy abrogates CD8⁺ T_N recovery after antibody-mediated CD8⁺ T cell depletion.

Analysis of CD8⁺ T_N and T_M population dynamics, including T_CM, T_TrM and T_EM subsets after mAb cM-T807 treatment in RM with complete initial CD8⁺ T cell depletion in blood that were previously subjected to thymectomy (n=8) or sham surgery (n=8). Results (mean + SEM) are shown as change from baseline value, with baseline represented as 100% and subsequent changes are shown relative to this baseline value determined as the average of absolute counts (see materials and methods) at days -14, -7 and 0 relative to the first dose of cM-T807.