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. Author manuscript; available in PMC: 2015 Oct 23.
Published in final edited form as: Org Lett. 2012 Jul 5;14(14):3568–3571. doi: 10.1021/ol300728a

Figure 3.

Figure 3

Cell survival studies and LC50 determination. Survival of Hela and HeLa HSV1-mNLS-sr39TK cells grown in the presence of increasing amounts of either 5 (3A, top) or 6 (3B, bottom). Cells grown in the presence of vehicle alone served as negative control; data for cell survival in the presence of either 5 or 6 was plotted as a percent of vehicle control. LC50 (μM): 3A. 5, HeLa: >> 100 μM, HeLa HSV-1-mNLS-sr39TK: 0.00078 μM; 3B. 6, HeLa: >> 100 μM, HeLa HSV-1-mNLS-sr39TK: 0.074 μM). Each point represents the mean value of sextuplicate determinations; bars represent ± standard deviation when larger than symbol.