Table 2. Univariate regression analysis identifying covariables associated with cIMT.
| Variable | Controls n = 117 | RA patients n = 243 | Total population n = 360 | |||
|---|---|---|---|---|---|---|
| B (95% CI) | P-value | B (95% CI) | P-value | B (95% CI) | P-value | |
| Age (yr) | 0.006 (0.004–0.007) | <0.001 | 0.006 (0.005–0.007) | <0.001 | 0.006 (0.005–0.007) | <0.001 |
| Male sex | 0.021 (-0.029–0.071) | 0,243 | 0.050 (0.018–0.082) | 0.002 | 0.041 (0.014–0.068) | 0.003 |
| Smoking | 0.097 (0.028–0.166) | 0.006 | 0.016 (-0.021–0.053) | 0.403 | 0.034 (0.001–0.067) | 0.044 |
| BMI (kg/m2) | 0.005 (-0.002–0.012) | 0.139 | 0.005 (0.001–0.008) | 0.010 | 0.004 (0.001–0.007) | 0.006 |
| Waist (cm) | 0.002 (0.000–0.004) | 0.101 | 0.002 (0.001–0.003) | <0.001 | 0.002 (0.001–0.003) | <0.001 |
| BPs (mmHg) | 0.002 (0.001–0.004) | 0.009 | 0.003 (0.002–0.004) | <0.001 | 0.003 (0.002–0.003) | <0.001 |
| BPd (mmHg) | 0.000 (-0.003–0.003) | 0.963 | 0.004 (0.002–0.005) | <0.001 | 0.003 (0.001–0.004) | <0.001 |
| LDL-C (mmol/l) | 0.043 (0.019–0.066) | <0.001 | 0.034 (0.020–0.049) | <0.001 | 0.037 (0.025–0.050) | <0.001 |
| HDL-C (mmol/L) | -0.010 (-0.066–0.047) | 0.740 | -0.010 (-0.040–0.020) | 0.511 | -0.010 (-0.037–0.017) | 0.476 |
| Apo AI (g/l) | 0.013 (-0.065–0.091) | 0.750 | -0.016 (-0.059–0.027) | 0.473 | -0.010 (-0.048–0.028) | 0.610 |
| Apo B (g/l) | 0.114 (0.034–0.194) | 0.005 | 0,131 (0.075–0.187) | <0.001 | 0.126 (0.081–0.172) | <0.001 |
| TG (mmol/l)* | 0.013 (-0.020–0.045) | 0.441 | 0.026 (0.003–0.049) | 0.026 | 0.022 (0.003–0.040) | 0.022 |
| Glucose (mmol/l)* | 0.009 (-0.019–0.036) | 0.536 | 0.044 (0.016–0.072) | 0.002 | 0.021 (0.001–0.040) | 0.029 |
| CRP (mg/dl) | -0.000 (-0.014–0.014) | 0.964 | 0.001 (-0.001–0.003) | 0.504 | 0.000 (-0.002–0.002) | 0.731 |
| Creatinin (umol/l) | 0.001 (-0.001–0.003) | 0.549 | 0.002 (0.001–0.003) | 0.002 | 0.001 (0.001–0.003) | 0.002 |
| Absence of RA | - | - | - | - | 0.017 (-0.010–0.045) | 0.220 |
| Anti-CCP | - | - | 0.033 (-0.004–0.070) | 0.078 | ||
| Rheumatoid factor | - | - | 0.020 (-0.013–0.053) | 0.231 | ||
| Erosive Disease | - | - | 0.020 (-0.011–0.051) | 0.212 | ||
| DAS28 | - | - | 0.005 (-0.009–0.019) | 0.494 | ||
| DAS28CRP | - | - | -0.001 (-0.017–0.015) | 0.902 | ||
| Disease duration | - | - | 0.002 (0.001–0.004) | 0.012 | ||
| Methotrexate | - | - | 0.001 (-0.036–0.037) | 0.976 | ||
| Biological agents | - | - | -0.07 (-0.039–0.024) | 0.651 | ||
RA = Rheumatoid arthritis, BPs = systolic blood pressure, BPd = diastolic blood pressure, TG = triglycerides, DAS28 = RA disease activity score 28 joints