TABLE 2.
ZNF638 interacting proteins implicated in pre-mRNA splicing identified by mass spectrometry analysis
Gene Symbol | Protein Name | Uniprot Accession Number | Number of Peptide Matches | References |
Cpsf6 | Cleavage and polyadenylation specificity factor subunit 6 | Q6NVF9 | 1 | (36) |
Ddx1 | ATP-dependent RNA helicase DDX1 | Q91VR5 | 30 | (36) |
Ddx17 | Probable ATP-dependent RNA helicase DDX17 | Q501J6 | 10 | (33, 36) |
Ddx3× | ATP-dependent RNA helicase DDX3× | Q62167 | 4 | (33, 36) |
Ddx46 | Probable ATP-dependent RNA helicase DDX46 | Q569Z5 | 3 | (33, 34, 36, 53) |
Ddx5 | Probable ATP-dependent RNA helicase DDX5 | Q61656 | 20 | (33–36, 54) |
Ddx50 | ATP-dependent RNA helicase DDX50 | Q99MJ9 | 3 | (36) |
Dhx15 | Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 | O35286 | 6 | (33, 36, 55) |
Dhx30 | Putative ATP-dependent RNA helicase DHX30 | Q99PU8 | 4 | (36) |
Dhx9 | ATP-dependent RNA helicase A | O70133 | 5 | (33, 34, 36) |
Elavl1 | ELAV-like protein 1 | P70372 | 2 | (34, 36) |
Ewsr1 | RNA binding protein EWS | Q61545 | 10 | (33, 36) |
Fbl | rRNA 2’-O-methyltransferase fibrillarin | P35550 | 2 | (33) |
Fus | RNA binding protein FUS | P56959 | 18 | (33, 34, 36) |
Gpatch1 | G patch domain-containing protein 1 | Q9DBM1 | 1 | (35) |
Hist1 h1c | Histone H1.2 | P15864 | 2 | (33) |
Hnrnpa0 | Heterogeneous nuclear ribonucleoprotein A0 | Q9CX86 | 1 | (33, 36) |
Hnrnpa1 | Heterogeneous nuclear ribonucleoprotein A1 | P49312 | 14 | (33–38) |
Hnrnpa2b1 | Heterogeneous nuclear ribonucleoproteins A2/B1 | O88569 | 25 | (33–36, 39, 40) |
Hnrnpa3 | Heterogeneous nuclear ribonucleoprotein A3 | Q8BG05 | 15 | (33–36) |
Hnrnpab | Heterogeneous nuclear ribonucleoprotein A/B | Q99020 | 8 | (36) |
Hnrnpd | Heterogeneous nuclear ribonucleoprotein D0 | Q60668 | 4 | (33, 36) |
Hnrnpl | Heterogeneous nuclear ribonucleoprotein L | Q8R081 | 6 | (33, 35, 36, 56) |
Hnrnpm | Heterogeneous nuclear ribonucleoprotein M | Q9D0E1 | 4 | (33, 35, 36, 57) |
Hnrnpr | Putative uncharacterized protein | Q3UZI0 | 10 | (36) |
Hnrnpu | Heterogeneous nuclear ribonucleoprotein U | Q8VEK3 | 49 | (33–36) |
Hnrpll | Heterogeneous nuclear ribonucleoprotein L-like | Q921F4 | 1 | (41, 42) |
Hspa5 | 78 kDa glucose-regulated protein | P20029 | 19 | (33) |
Hspa8 | Heat shock cognate 71 kDa protein | P63017 | 3 | (36) |
Igf2bp3 | Insulin-like growth factor 2 mRNA binding protein 3 | Q9CPN8 | 10 | (36) |
Ilf3 | Interleukin enhancer binding factor 3 | Q9Z1 × 4 | 3 | (33, 34, 36) |
Matr3 | Matrin-3 | Q8K310 | 1 | (33, 36) |
Ncbp1 | Nuclear cap binding protein subunit 1 | Q3UYV9 | 1 | (33–36, 58) |
Ncl | Nucleolin | P09405 | 23 | (36) |
Nono | Non-POU domain-containing octamer binding protein | Q99K48 | 1 | (33, 36, 57, 59, 60) |
Nop56 | Nucleolar protein 56 | Q9D6Z1 | 3 | (33) |
Nop58 | Nucleolar protein 58 | Q6DFW4 | 1 | (33) |
Npm1 | Nucleophosmin | Q61937 | 2 | (36) |
Nxf1 | Nuclear RNA export factor 1 | Q99JX7 | 1 | (33, 36) |
Pabpc1 | Polyadenylate binding protein, cytoplasmic 1 | P29341 | 4 | (35, 61) |
Ppp1ca | Serine/threonine-protein phosphatase PP1-α catalytic subunit | P62137 | 2 | (36) |
Ppp1r10 | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | Q80W00 | 12 | (33) |
Rbm15 | Putative uncharacterized protein | Q3THK4 | 1 | (36) |
Rbm39 | RNA binding protein 39 | Q8VH51 | 2 | (21, 33, 34) |
Rbmx | Heterogeneous nuclear ribonucleoprotein G | O35479 | 1 | (33, 35, 36, 62) |
Rpl7a | 60S ribosomal protein L7a | P12970 | 4 | (33) |
Rplp0 | 60S acidic ribosomal protein P0 | P14869 | 4 | (33) |
Rps2 | 40S ribosomal protein S2 | P25444 | 2 | (33) |
Rps3a | 40S ribosomal protein S3a | P97351 | 3 | (33) |
Safb2 | Scaffold attachment factor B2 | Q80YR5 | 7 | (36) |
Sf1 | Splicing factor 1 | Q64213 | 2 | (33, 36, 63) |
Sf3b1 | Splicing factor 3B subunit 1 | Q99NB9 | 1 | (33–36, 64) |
Sfpq | Splicing factor, proline and glutamine rich | Q8VIJ6 | 34 | (33, 36, 65) |
Sltm | SAFB-like transcription modulator | Q8CH25 | 1 | (33) |
Srpk1 | Serine/threonine-protein kinase SRPK1 | O70551 | 1 | (66) |
Srsf4 | Serine/arginine-rich splicing factor 4 | Q8VE97 | 1 | (33, 36, 67) |
Srsf7 | Serine/arginine-rich splicing factor 7 | Q8BL97 | 1 | (33, 34, 36, 68) |
Syncrip | Heterogeneous nuclear ribonucleoprotein Q | Q7TMK9 | 23 | (35, 36, 69) |
Taf15 | TAF15 RNA polymerase II, TATA box binding protein-associated factor | Q8BQ46 | 3 | (36) |
Tdrd3 | Tudor domain-containing protein 3 | Q91W18 | 2 | (34) |
Tmpo | Lamina-associated polypeptide 2, isoforms α/zeta | Q61033 | 1 | (33) |
U2surp | U2 snRNP-associated SURP motif-containing protein | Q6NV83 | 1 | (33, 34) |
Wbp11 | WW domain binding protein 11 | Q923D5 | 1 | (36, 70) |
Xrn2 | 5′-3′ exoRNase 2 | Q9DBR1 | 2 | (36) |
Zfr | Zinc finger RNA binding protein | O88532 | 6 | (33, 36) |
Znf638 | Zinc finger protein 638 | Q61464 | 27 | (33) |