TABLE 1.

Plasma cholesterol, HDL cholesterol, and triglycerides of WT or LDLR^−/− mice

	Total Cholesterol	HDL Cholesterol	Triglycerides
Males	mg/dl	mg/dl	mg/dl
WT	93.3 ± 3.8 (30)	83.8 ± 3.6 (27)	105.8 ± 7.0 (20)
LDLR−/−−/−	264.8 ± 16.9 (31)	92.7 ± 4.7 (28)	249.1 ± 26.1 (23)
P	<0.0001	0.0705	<0.0001
Females
WT	89.9 ± 4.4 (30)	78.2 ± 3.0 (30)	122.5 ± 8.2 (24)
LDLR−/−−/−	229.7 ± 8.8 (22)	75.1 ± 3.3(22)	161.2 ± 8.5 (17)
P	<0.0001	0.251	0.0014

^−/−Male or female WT or LDLR^−/− mice were fasting for 4 h. Thereafter, blood was harvested and plasma was analyzed as outlined in Materials and Methods. Values are means ± SEM; the number of mice is given in parentheses.