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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Immunol Allergy Clin North Am. 2015 Mar 6;35(2):247–260. doi: 10.1016/j.iac.2015.01.009

Table 3.

Red meat challenges in patients with or without IgE specific for galactose-alpha-1, 3-galactose

Group Time to Symptoms Urticaria* Treatment
Tryptase Elevation
Antihistamine Epinephrine Prednisone
Allergic (n=12] 2.45-5.00 hr 10/12 9/12 2/12 4/12 3/11#
Controls (n=13) NR 0/13$ 0/13 0/13 0/13 0/13
*

Urticaria was characterized by flushing

Flushing with intestinal spasms was observed in only one of these subjects

#

Tryptase rises: i) 4.7 to 10.7 ng/mL, ii) 4.2 to 20,1 ng/mL, iii) 6.2 to 183 ng/mL

$

p<0.001

Data from Commins SP, James H, Stevens W, et al: Delayed clinical and ex vivo response to mammalian meat in patients with IgE to galactose-alpha-1, 3-galactose. JACI 2014, 134:108-115.