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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Vascul Pharmacol. 2015 Aug 8;73:115–123. doi: 10.1016/j.vph.2015.08.007

Fig. 3. The effects of Ang-(1-7) on regulating gene expressions and cytokines release of HBVSMCs.

Fig. 3

Ang II induced the up-regulation of NFκB (A) and down-regulation of IκBα (B) in HBVSMCs. In addition, Ang II induced the release of TNF-α (C), MCP-1 (D) and IL-8 (E) from HBVSMCs. Ang-(1-7) counteracted these effects of Ang II, which could be aborted by A-779. **P< 0.01 vs. veh; ++P< 0.01 vs. Ang II, ##P< 0.01 vs. Ang II + Ang-(1-7), n=6/group. TNF-α: tumor necrosis factor; MCP-1: monocyte chemoattractant protein 1; IL-8: interleukin-8.