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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: J Allergy Clin Immunol. 2015 Jul;136(1):3–13. doi: 10.1016/j.jaci.2015.03.048

Table 4.

Pre-existing factors and changes that could be relevant to the rise of peanut allergy in the USA: 1990 to the present

I. Differences in the preparation of peanut products:
  1. Roasted vs. boiled

  2. Emulsified peanut products in the USA

II. Delayed oral consumption of peanut proteins:
  1. Comparison of Israel and London

  2. American Academy of Pediatrics policy regarding avoiding peanut products

III. Changes in skin as a result of daily bathing with soap or detergents:
  1. Removal of lipids from the skin

  2. Other damage that could allow increased skin penetration

IV. Changes in vaccination policy:
  1. Increase in frequency

  2. Change from cellular to acellular pertussis