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a) Structure of Curcumin. b) Design of CRANAD-28 through pyrazole replacement. c) The synthetic route for CRANAD-28. d) The excitation/emission spectra of CRANAD-28 and -44. e) Fluorescence responses of CRANAD-28 with Aβ40 aggregates, Aβ40 monomers and Aβ42 monomers. For Aβ42 dimers and oligomers, the spectra are shown in SI Fig.1.
