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. Author manuscript; available in PMC: 2015 Oct 23.
Published in final edited form as: Crit Care Med. 2015 Jan;43(1):149–158. doi: 10.1097/CCM.0000000000000624

Figure 4.

Figure 4

Delayed xenon treatment following trauma reduces injury 24 hours after trauma. (A) Typical cresyl-violet stained slices, 2.2 mm posterior to Bregma, showing primary injury 15 min after trauma, control injury and xenon-treated injury at 24 hours after trauma. In example shown xenon treatment was delayed until 1 hour after trauma. (B) Xenon-treated animals (grey bars) received 75% xenon : 25% oxygen for 3 hours duration starting at 15 minutes, 1 hour, 3 hours or 6 hours after trauma. Control animals (white bar) received 75% nitrogen:25% oxygen. Contusion volume was measured 24 hours after trauma. Bars represent mean values and error bars are standard errors (n=22, control; n=9, xenon 15 min; n=8, xenon 1 hr; n=9, xenon 3 hr; n=9, xenon 6 hr) * = p<0.05; ** = p<0.01 compared to control.