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. Author manuscript; available in PMC: 2015 Oct 24.
Published in final edited form as: Lancet Neurol. 2010 Jan 8;9(2):149–158. doi: 10.1016/S1474-4422(10)70002-8

Figure 4. Reliability of imaging classification on repeat testing.

Figure 4

Probabilities of idiopathic Parkinson’s disease and atypical parkinsonian syndrome computed from the initial and repeat scans of 22 patients. Values from the two scans from each patient are connected by solid lines. Significant agreement (p<0·0001) was found between the image-based classifications from the two scans for these patients. Probability of atypical parkinsonian syndrome is the inverse of that for idiopathic Parkinson’s disease. (A) Five patients clinically diagnosed with idiopathic Parkinson’s disease who were drug-naive at the time of the initial scan and who were rescanned after 3 months of oral carbidopa plus levodopa treatment. (B) 14 patients with clinical idiopathic Parkinson’s disease who were scanned twice in the off-state. Six patients (blue squares) were drug-naive at baseline and eight (red triangles) were receiving chronic oral treatment at the time of the first scan. All were receiving levodopa treatment chronically at the time of repeat scanning. (C) Three patients clinically diagnosed with multiple system atrophy who had repeat scanning.