Table 1. Compositions of Magnetically Purified Composite NanoCarriers (CNCs) a.
| Co-Core Excipient | Globule Size (d-nm) | Purified CNC Composition | Relative Number Density WRT IONC | Yield (wt %) | ||
|---|---|---|---|---|---|---|
| IONC (wt %) | Co-Core Excipient (wt %) | Stabilizer (wt %) | ||||
| Original Formulation | - | 8 | 42 | 50 | - | - |
| Hostasol Yellow | 1 | 25 ± 4.8 | 45.6 ± 1.6 | 29.5 ± 3.2 | 15,000 | 28.4 ± 1.3 |
| 11k PLA | 4 | 22.0 ± 0.9 | 49.2 ± 1.5 | 31.0 ± 0.7 | 800 | 31.7 ± 0.5 |
| 106k PLA | 9 | 15.0 ± 1.1 | 61.3 ± 1.3 | 25.5 ± 2.5 | 80 | 42.1 ± 0.9 |
a
CNCs were prepared from initial formulations comprising 50 wt% PEG-b-PLA, 8 wt% IONC, and 42 wt% core co-excipient.