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. 2015 Oct 20;11(10):e1005230. doi: 10.1371/journal.ppat.1005230

Fig 1. HCMV gH/gL antibody binding competition.

Fig 1

HCMV gH/gL antibody binding competition in an ELISA assay. On the x-axis are the individual capturing monoclonal antibodies; on the y-axis is the optical density determined spectrophotometrically at 450 nm. Each graph represents the results from addition of one biotinylated detection antibody. Significant reduction in signal indicates competition between the capturing antibody and the detection antibody. (A) Binding of 3G16 or MSL-109 does not interfere with 13H11 binding indicating that 13H11 and 3G16 or MSL-109 do not compete for binding of gH. (B) Binding of 3G16 but not of 13H11, interferes with MSL-109 binding, indicating that 3G16 and MSL-109 compete.