Table 1.
Cytokines produced by Her-2 responders in old breast cancer patients
| Old (n = 38) | |||||
|---|---|---|---|---|---|
| CD4 | Response | No. of patients | % Dead | 5-year survival rate | P value |
| TNF | Yes | 27 | 37 | 60 | 0.1 |
| No | 11 | 18 | 81 | ||
| IFN-γ | Yes | 23 | 43 | 57 | 0.1 |
| No | 15 | 13 | 84 | ||
| IL-5 | Yes | 7 | 57 | 43 | 0.1 |
| No | 31 | 23 | 73 | ||
| IL-10 | Yes | 3 | 33 | 67 | 0.8 |
| No | 35 | 31 | 65 | ||
| IL-2 | Yes | 13 | 46 | 54 | 0.3 |
| No | 25 | 24 | 74 | ||
| IL-17 | Yes | 3 | 67 | 33 | 0.3 |
| No | 35 | 29 | 70 | ||
| IL-5 and or IL-17 | Yes | 10 | 50 | 29 | 0.01 |
| No | 28 | 25 | 76 | ||
| CD8 | |||||
| TNF | Yes | 14 | 7 | 93 | 0.01 |
| No | 24 | 46 | 52 | ||
| IFN- γ | Yes | 13 | 23 | 76 | 0.3 |
| No | 25 | 36 | 62 | ||
| IL-10 | Yes | 2 | 50 | 50 | 0.7 |
| No | 36 | 31 | 68 | ||
| IL-2 | Yes | 1 | 0 | 100 | 0.5 |
| No | 37 | 32 | 66 | ||
Results of survival analysis according to Kaplan Meier method and p values from Mantel-Cox (log-rank) test