Table 2.
Factors associated with depression (bivariate and multivariate) analysis, at UoGH, 2014
| Explanatory variables | Depression Yes N (%) No N (%) |
COR (95 % CI) | AOR (95 % CI) | P value |
|---|---|---|---|---|
| Age | ||||
| 18–24 | 66 (40) 99 (60) | 0.67 (0.305, 1.455) | ||
| 25–34 | 51 (41.5) 72 (58.5) | 0.71 (0.318, 1.577) | ||
| 35–44 | 51 (58.6) 36 (41.4) | 1.42 (0.616, 3.259) | ||
| ≥45 | 15 (50) 15 (50) | 1 | ||
| Educational status | ||||
| Can’t read and write | 57 (48.7) 60 (51.3) | 5.70 (2.233, 14.551) | 8.32 (4.826, 14.294)** | <0.001 |
| Primary | 90 (46.2) 105 (53.8) | 5.14 (2.072, 12.763) | 6.02 (3.727, 9.292)** | <0.001 |
| Secondary | 30 (58.8) 21 (41.2) | 8.57 (3.064, 23.974) | 4.00 (4.102, 8.251)** | 0.005 |
| College and above | 6 (14.3) 36 (85.7) | 1 | 1 | |
| Social support | ||||
| High | 105 (42.2) 144 (57.8) | 1 | ||
| Moderate | 42 (45.2) 51 (54.8) | 1.13 (0.699, 1.825) | ||
| Low | 36 (57.142.9) 27 (6.7) | 1.83 (1.046, 3.197) | ||
| Perceived stress | ||||
| Low | 51 (27) 138 (73) | 1 | 1 | <0.001 |
| High | 132 (61.1) 84 (38.9) | 4.25 (2.789, 6.484) | 6.21 (3.691, 10.442)** | |
| Age at onset of the disease in year | ||||
| <6 | 15 (83.3) 3 (0.716.7) | 2.50 (0.625, 9.996) | 5.29 (4.086, 15.894)** | <0.001 |
| 6–11 | 24 (53.3) 21 (46.7) | 0.57 (0.244, 1.341) | 0.95 (0.287, 3.169) | 0.939 |
| 12–17 | 36 (32.4) 75 (67.6) | 0.24 (0.115, 0.501) | 0.55 (0.213, 1.413) | 0.214 |
| 18–24 | 45 (40.5) 66 (59.5) | 0.34 (0.165, 0.705) | 0.85 (0.343, 2.153) | 0.734 |
| 25–34 | 33 (44) 42 (56) | 0.39 (0.182, 0.848) | 0.84 (0.330, 2.153) | 0.720 |
| ≥35 | 30 (66.7) 15 (33.3) | 1 | 1 | |
| Seizure frequency per year | ||||
| 0 | 21 (25) 63 (75) | 1 | 1 | 1 |
| 1–11 per year | 147 (50.5) 144 (49.5) | 3.06 (1.776, 5.280) | 1.34 (1.414, 4.360)** | 0.022 |
| ≥12per year | 15 (50) 15 (50) | 3.00 (1.257, 7.157) | 7.83 (3.523, 17.400)** | <0.001 |
| Therapy (number of drug) | ||||
| Mono-pharmacy | 132 (42.7) 177 (57.3) | 1 | 1 | <0.001 |
| Poly-pharmacy | 51 (53.1) 45 (46.9) | 5.34 (1.484, 19.389) | 7.63 (2.741, 21.264)** | |
| Difficulties of adherence to AEDs | ||||
| Yes | 81 (61.4) 51 (38.6) | 2.66 (1.736, 4.083) | 4.80 (2.568, 8.964)** | <0.001 |
| No | 102 (37.4) 171 (62.6) | 1 | 1 | |
| Family history of mental illness | ||||
| Yes | 9 (50) 9 (50) | 1.22 (0.476, 3.151) | ||
| No | 174 (40.3) 258 (59.7) | 1 | ||
** Statistically significant using a forward stepwise regression method with p value of Hosmer and Lemeshow goodness fit test 0.344