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(A) Injury groups: sham (craniectomy + laminectomy) (n = 9); spinal cord inury (SCI) + craniectomy (n =10), traumatic brain injury (TBI) + laminectomy (n = 10), SCI + contralateral TBI (n = 10), SCI + ipsilateral TBI (n=10). (B) Sequence of surgical procedures for producing the combined SCI + TBI model. (C) Behavioral testing was done 2, 7, 14, 21, 28, 35 and 42 days after the injury, and then rats were euthanized.
