Table 1.
Characteristic | All (n = 876) | Anaemia only* (n = 639) | Symptomatic (n = 237) | P |
---|---|---|---|---|
Participant | ||||
Age | 24.6 ± 5.4 | 24.5 ± 5.4 | 24.8 ± 5.5 | 0.446 |
Primigravida | 48.3 (423) | 47.3 (302) | 51.1 (121) | 0.318 |
Fundal height at enrolment | 22 [6–27] | 22 [6–27] | 21 [6–27] | 0.002 |
Rural dweller | 70.6 (618) | 70.9 (453) | 69.6 (165) | 0.714 |
SPAZ-IPTp | 49.9 (437) | 51.6 (330) | 45.2 (107) | 0.088 |
All (n = 1162) | Anaemia only* (n = 854) | Symptomatic (n = 308) | ||
---|---|---|---|---|
Episode | ||||
RDT | ||||
HRP2 + | 5.3 (62) | 2.1 (18) | 14.3 (44) | <0.001 |
HRP2 + pLDH + | 4.5 (52) | 1.2 (10) | 13.6 (42) | <0.001 |
pLDH + | 1.8 (21) | 0.8 (7) | 4.5 (14) | <0.001 |
Light microscopy | ||||
P. falciparum | 11.5 (133) | 5.6 (48) | 27.6 (85) | <0.001 |
Asexual parasite density | 5141 (1437; 16–123,484) | 2237 (441; 39–19,372) | 6731 (2418; 16–123,484) | 0.001 |
<200 parasites/µL | 21.1 (28/133) | 29.2 (14/48) | 16.5 (14/85) | 0.085 |
P. vivax | 0.9 (10) | 0.9 (8) | 0.7 (2) | 0.480 |
Asexual parasite density | 434 (96; 16–3341) | 470 (60; 16–3341) | 288 (288; 143–432) | <0.001 |
<200 parasites/µL | 80.0 (8/10) | 87.5 (7/8) | 50.0 (1/2) | 0.378 |
qPCR positive | ||||
P. falciparum** | 14.7 (171) | 10.1 (86) | 27.6 (85) | <0.001 |
P. vivax** | 2.2 (25) | 2.5 (21) | 1.3 (4) | 0.358 |
Descriptive data on participant pregnancy characteristics of all women tested and by those tested specifically for anaemia or symptomatic malaria criteria. Descriptive data of rapid diagnostic test results, light microscopy and qPCR by all women tested, and and by those tested specifically for anaemia or symptomatic malaria criteria. Numbers are mean ± standard deviation, median [range], geometric mean (median; range) or % (n). SPAZ-IPTp, intermittent preventive treatment with sulfadoxine-pyrimethamine plus azithromycin; HRP2, histidine-rich protein 2; pLDH, genus-specific lactate dehydrogenase
* Includes 81 women that were tested for mild anaemia (Hb ≥90 and <110 g/L) or for other reasons
** 6 women had mixed P. falciparum/P. vivax infections