Table 4.
Pre- and Post-Kidney Transplantation (KT) Factors Associated with Trajectories of Frailty
| Pre-KT Model | Pre-KT Model | |||
|---|---|---|---|---|
| Without Pre-KT Frailty | With Pre-KT Frailty | Without Pre-KT Frailty | With Pre-KT Frailty | |
| Factor | Relative Risk (95% Confidence Interval) | |||
| Frail at KT | — | 1.53 (1.33–1.77) | — | 1.49 (1.29–1.72) |
| Male recipient | 0.97 (0.85–1.12) | 1.01 (0.88–1.15) | 0.95 (0.83–1.10) | 0.99 (0.87–1.13) |
| Aged ≥65 | 1.14 (0.97–1.33) | 1.12 (0.96–1.29) | 1.14 (0.98–1.33) | 1.12 (0.97–1.29) |
| Black | 0.99 (0.86–1.14) | 0.98 (0.86–1.12) | 0.97 (0.84–1.12) | 0.96 (0.84–1.10) |
| Live donor recipient | 0.68 (0.58–0.80) | 0.70 (0.60–0.81) | 0.72 (0.61–0.84) | 0.73 (0.62–0.84) |
| Body mass index (per 5 kg/m2) | 1.01 (0.96–1.08) | 1.01 (0.95–1.07) | 1.01 (0.95–1.07) | 1.00 (0.95–1.06) |
| Previous transplantation | 1.14 (0.95–1.38) | 1.13 (0.95–1.35) | 1.17 (0.97–1.41) | 1.14 (0.96–1.36) |
| Diabetes mellitus | 1.23 (1.05–1.45) | 1.26 (1.09–1.47) | 1.23 (1.05–1.44) | 1.26 (1.08–1.46) |
| Panel Reactive Antibody score 0 | 0.92 (0.80–1.06) | 0.91 (0.80–1.04) | 0.94 (0.81–1.08) | 0.92 (0.81–1.05) |
| No human leukocyte antibody mismatches | 0.85 (0.62–1.17) | 0.90 (0.66–1.22) | 0.87 (0.64–1.19) | 0.91 (0.67–1.23) |
| Time on dialysis (per year) | 1.00 (0.98–1.02) | 1.00 (0.98–1.02) | 1.00 (0.98–1.02) | 1.00 (0.98–1.02) |
| Delayed graft function | — | — | 1.30 (1.10–1.53) | 1.22 (1.04–1.43) |
| Acute rejection | — | — | 1.10 (0.74–1.64) | 1.14 (0.78–1.67) |