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. Author manuscript; available in PMC: 2016 Oct 21.
Published in final edited form as: Bioconjug Chem. 2015 Sep 10;26(10):2118–2124. doi: 10.1021/acs.bioconjchem.5b00414

Table 1.

Stepwise Chromium Reduction in a Single Production Batch Quantified by MP-AES Hold-Back Measurements

Cr mass (μg) step separation factor cumulative separation factor
dissolved target (4.05 ± 0.04) × 103 - -
after col. #1 360 ± 18 601 ± 31 (6.0 ± 0.3) × 102
after col. #2 3.82 ± 0.19 80 ± 6 (4.8 ± 0.4) × 104
after col. #3 0.083 ± 0.008 42 ± 5 (2.0 ± 0.3) × 106