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. Author manuscript; available in PMC: 2016 Oct 21.
Published in final edited form as: Bioconjug Chem. 2015 Sep 10;26(10):2118–2124. doi: 10.1021/acs.bioconjchem.5b00414

Table 3.

Radiolabeling Efficiency of 52Mn-DOTA-TRC105 as a Function of Antibody Mass and Time as Measured by Thin Layer Chromatographya

mAb mass (μg/MBq) 20 min 40 min 60 min
2.7 85% 89% 95%
6.8 98% 93% 99%
13.5 99% 95% 98%
27.0 99% 93% 100%
a

Reactions took place at 37 °C in a pH 4.0–4.5 NaOAc buffered solution.