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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Neurosci Res. 2015 Aug 31;93(12):1849–1864. doi: 10.1002/jnr.23638

Figure 1. Behavioral measures of executive function.

Figure 1

The performance of each mouse was measured during and following weekly administration of increasing doses of MPTP. (A) location-correct responses during the cue revealed that mice administered MPTP (n=14) failed to learn the task compared to the vehicle treated mice (n=11), while (B) latency to respond correctly following the onset of the cue increased progressively with the MPTP doses. (C) The precue period decreased significantly compared to the vehicle group following the 3rd and 4th week of MPTP administration. Values are means ± S.E.M. *p<0.01 versus vehicle group; **p<0.01 versus 32 mg/kg dose.