Table 4.
Relationship between uteroplacental flow and the analyzed biomarkers.
| Normal umbilical and uterine flow (n: 48) |
Normal uterine or umbilical flow (n: 17) |
Abnormal umbilical and uterine flow (n: 11) |
Statistical significance | |
|---|---|---|---|---|
| sFlt-1 median (min–max) | 2107 (308–16573) |
8374 (222–25538) |
16241 (2350–28182) |
P0 < 0.001 |
|
| ||||
| PlGF median (min–max) | 195.25 (10.98–2564.0) |
42.77 (10.39–796.90) |
41.07 (10.15–247.10) |
P0 < 0.001 |
|
| ||||
| Ratio median (min–max) | 9.94 (1.04–439.37) |
136.26 (1.86–2457.94) |
407.68 (9.51–2619.11) |
P0 < 0.001 |
P0 = Kruskal Wallis; Mann Whitney P1 = normal versus partially altered flow; P2 = normal versus altered flow; P3 = partially altered flow versus altered flow.
sFlt-1: P1 = 0.011; P2 < 0.001; P3 = 0.025. PlGF: P1 = 0.017; P2 < 0.001; P3 = 0.264. Ratio PlGF/sFlt-1: P1 = 0.003; P2 < 0.001; P3 = 0.025.