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. 2015 Oct 20;15:749. doi: 10.1186/s12885-015-1726-7

Table 2.

Histopathological features in gastric cancers with different HER2 status

HER2(+) HER2(-) P value
N 9 36
Gender (M/F) 6/3 23/13 0.876
Age (mean ± SD) 60.3 ± 10.7 61.6 ± 11.2 0.755
Diameter (mean ± SD) 5.11 ± 2.89 5.11 ± 2.21 1.000
Diameter (<3 cm/>3 cm) 2/7 10/27 0.768
Diameter (<4 cm/>4 cm) 5/4 14/22 0.365
T stage (1/2/3/4) 0/2/6/1 6/5/20/5 0.569
N stage (0/1-3) 2/7 9/27 0.862
M stage (0/1) 8/1 35/1 0.278
TNM stage (I/II/III/IV) 1/2/5/1 6/11/18/1 0.686
Lauren classification (intestinal/ mixed/diffuse type) 6/1/2 5/3/28 0.003*
Pathologic type(adenocarcinoma /signet ring cell cancer) 7/2 30/6 0.697
Differentiation degree of adenocarcinomas (poor/poor-mod/mod/mod-well)§ 4/2/1/0 12/9/7/2 0.784
Overall differentiation degree (poor/poor-mod/mod/mod-well) 6/2/1/0 18/9/7/2 0.758
Location (cardia&fundus/cardia&body/ body/body&antrum/antrum) 2/2/0/2/3 13/2/3/2/16 0.209

§poor, poorly; poor-mod, poorly to moderately; mod, moderately; mod-well, moderately to well; ‡ signet ring cell cancer was treated as poorly differentiated; * < 0.05