Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mice immunized with rVtp are protected from infection by tick bite only when challenged with Borrelia hermsii producing the same Vtp antigenic type
| Challenge strain | Vaccine Type | No. Infected / No. Total |
|---|---|---|
| B. hermsii DAH | Adjuvant Only | 5/5 |
| rVtp DAH | 0/5* | |
| rVtp LAK-3 | 5/5 | |
| B. hermsii LAK-3 | Adjuvant Only | 5/5 |
| rVtp DAH | 5/5** | |
| rVtp LAK-3 | 0/5* |
*Significantly different, Fisher’s exact test, p = 0.0003
**One mouse infected during second challenge
