Table 1.
Relationship between clinicopathological characteristics, t-rpS6, p-rpS6 expressions and survival time (Log-rank)
| Factors | n (%) | Median survival time (months) | Log rank P | |
|---|---|---|---|---|
| Gender | Male | 244 (77.22) | 28 | 0.083 |
| Female | 72 (22.78) | 32 | ||
| Age/years | <60 | 130 (41.14) | 28 | 0.942 |
| ≥60 | 186 (58.86) | 31 | ||
| Histological type | ADC | 142 (44.94) | 23 | 0.146 |
| SCC | 132 (41.77) | 32 | ||
| Others | 42 (13.29) | 22 | ||
| Histological differentiation | Poor | 150 (47.47) | 25 | 0.008* |
| Moderate/Well | 166 (50.63) | 32 | ||
| Tumor size | T1 + T2 | 167 (52.85) | 36 | <0.001* |
| T3 + T4 | 149 (47.15) | 21 | ||
| Lymph node invasion | N0 | 138 (43.67) | 37 | <0.001* |
| N1 + N2 + N3 | 178 (56.33) | 25 | ||
| Distant metastasis | M0 | 294 (93.04) | 31 | 0.005* |
| M1 | 22 (6.96) | 17 | ||
| Stage | I | 87 (27.53) | 56 | <0.001* |
| II + III + IV | 229 (72.47) | 22 | ||
| t-rpS6 | P | 262 (82.91) | 28 | 0.230 |
| N | 54 (17.09) | 35 | ||
| p-rpS6 | P | 165 (52.22) | 20 | <0.001* |
| N | 151 (47.78) | 42 | ||
| p-rpS6/t-rpS6 | ≥0.67 | 188 (59.49) | 12 | <0.001* |
| <0.67 | 128 (40.51) | 48 | ||
t-rpS6 total rpS6; p-rpS6 phosphorylation of rpS6; ADC adenocarcinoma; SCC squamous cell carcinoma; P positive expression; N negative expression
*: P < 0.05