Table 2.

Genes Exhibiting cis eQTLs across Multiple Tissues at the Chromosome 5 Locus for LSKCD150⁻CD48⁻ Cells

Gene	Gene Position (bp)a	SNP	SNP Position (bp)a	GWAS p Valueb	eQTL p Value
Bone	Macrophage	Liver	Heart
Srd5a3	76569296-76584529	rs13478330	75857166	0.26	5.8 × 10−7	ns	ns	ns
		rs3153753	76574923	0.99	4.0 × 10−15	ns	ns	ns
		rs4225290	76583956	0.76	ns	ns	ns	5.0 × 10−8
		rs33559924	76254389	0.47	ns	ns	9.0 × 10−12	ns
		rs3697530	76575062	0.82	ns	ns	3.9 × 10−16	ns
		rs13478335	76955455	0.41	ns	2.0 × 10−17	ns	ns
Tmem165	76612905-76638270	rs4225290	76583956	0.76	ns	1.5 × 10−11	ns	ns
Exoc1	76958336-76999319	rs4225290	76583956	0.76	9.4 × 10−10	ns	ns	ns
		rs13478334	76817411	0.64	ns	9.4 × 10−12	ns	ns
		rs33139946	76913636	0.64	ns	9.4 × 10−12	ns	ns
		rs31555016	76915601	0.64	ns	9.4 × 10−12	ns	ns
		rs31555860	76921199	0.64	ns	9.4 × 10−12	ns	ns
		rs29561143	77013954	0.86	ns	ns	5.2 × 10−7	ns
Cep135	77075352-77075401	rs29824030	75977692	0.36	6.2 × 10−8	ns	ns	ns
		rs13478331	76154830	0.38	1.7 × 10−9	ns	ns	ns
Hopx	77516011-77544181	rs33077631	77509306	6.1 × 10−6	4.0 × 10−8	ns	ns	ns
		rs33175967	77511463	2.6 × 10−5	ns	ns	ns	6.2 × 10−19
		rs33750358	77534348	6.1 × 10−6	4.0 × 10−8	ns	ns	ns
		rs33117479	77536186	4.8 × 10−5	ns	1.6 × 10−6	3.4 × 10−18	ns

A genomic region ±1 Mb around the peak SNP for LSKCD150⁻CD48⁻ cells on chromosome 5 (rs29633853; bp position 77528483) was interrogated for the presence of cis eQTLs in multiple tissues using the UCLA Systems Genetics Resource (http://systems.genetics.ucla.edu/). Only genes exhibiting cis eQTLs in bone, macrophage, liver, or heart are listed. Ns, not significant.

^aBase pair (bp) positions of genes and SNPs are given according to NCBI build 37 of the reference mouse genome sequence.

^bp values are given from GWAS results that included all HMDP strains. See also Figure S4.