Table 4.

Cox multivariate analysis of GATA4 expression/promoter methylation and clinico-pathological features in pediatric AML

Variable	Odds ratio	EXP(B) 95 % CI	P
Cytogenetics
Favo vs. Inter and Unfavo	5.894	2.412 (1.185–4.909)	0.015
MRD
< 0.25 % vs. ≥0.25 %	16.241	5.986 (2.503–14.229)	0.000
Leukocyte (/μl)
> 10,000 vs. ≤10,000	0.485	1.225 (0.691–2.172)	0.486
FAB classification
M7 vs. M1–M6	6.645	2.630 (1.261–5.484)	0.010
GATA4 Expression
Low vs. High	2.765	1.657 (0.914–3.007)	0.096
GATA4 Methylation
Negative vs. Positive	1.885	0.661 (0.367–1.193)	0.170