Table 2. Desymmetrization of α-quaternary aldehyde 1 by isomerization-hydroacylations ^a .

^aReaction conditions: 0.1 mmol 1, x = 2.5, DCE (0.2 M), 40 °C, 4 h.

^bReaction conditions: 1 mmol 1c used.

^cReaction conditions: x = 5, DCE (0.33 M), 30 °C, 2 h.

^dReaction conditions: x = 6, DCE (0.33 M), 30 °C, 2 h.