. Author manuscript; available in PMC: 2015 Oct 24.

Published in final edited form as: Mod Pathol. 2015 Jul 31;28(10):1390–1399. doi: 10.1038/modpathol.2015.86

Table 1. KRAS, NRAS, RARF, and PRK3CA mutations in right-sided and left-sided colorectal cancers.

Location	Quadruple negative^a	KRAS	NRAS	BRAF	MAPK^b	PIK3CA	Only PIK3CA
Right (n = 116)	16 (14%)	64 (55%)	9 (8%)	26 (22%)	94 (81%)	20 (17%)	6 (5%)
Left (n = 176)	78 (44%)	75 (43%)	4 (2%)	9 (5%)	87 (49%)	25 (14%)	11 (6%)
	Po 0.001	P=0.04	P=0.04	Po 0.001	Po 0.001	P=0.48	P=0.70

No mutation detected in the KRAS, NRAS, BRAF, and PIK3CA genes.

Mutations in the KRAS, NRAS, and/or BRAF genes, including three rumors with concomitant KRAS and NRAS mutations and two tumors with concomitant KRAS and BRAF mutations in the right-sided colorectal cancers, and one tumor with concomitant KRAS and BRAF mutations in the left-sided colorectal cancers.