Table 6. Assessment of olefin geometry on α-helicity of linear peptides 21 and 23 and corresponding macrocycles 27 and 29 .

Entry	Compound	% α-helicity a
1	21	20.8
2	E-27	80.9
3	Z-27	71.0
4	23	7.5
5	E-29	21.2
6	Z-29	23.1

^aDetermined by circular dichroism.