Table 1.
Characteristics of HIV-1 infected pregnant women and comparison of those with and without ZDV-resistance mutations at delivery.
| Total (n=50) | Subjects with ZDV Mutations at Delivery (n=7) |
Subjects without ZDV Mutations (n=43) |
p-value | ||
|---|---|---|---|---|---|
| Age (years) |
Median | 27.5 | 30 | 27.3 | 0.5 |
| IQR | 24 – 30.3 | 26.3-31.3 | 23.9-30.3 | ||
| Plasma HIV RNA at study entry (c/mL) |
Median | 12,464 | 14,366 | 11,500 | 0.72 |
| IQR | 7,635 – 30,150 | 9,760-34,000 | 7,670-25,550 | ||
| Plasma HIV RNA at delivery (c/mL) |
Median | 7,250 | 15,586 | 7,100 | 0.16 |
| IQR | 4,500 – 14,771 | 8,704-35,400 | 4,610-13,702 | ||
| CD4+ T- cells at study entry (cells/μL) |
Median | 424 | 365 | 430 | 0.31 |
| IQR | 334 – 528 | 304-457 | 344-538 | ||
| ZDV duration (weeks) |
Median | 10.7 | 11.85 | 10.57 | 0.51 |
| IQR | 10 – 12.28 | 9.64-13.78 | 10-12 | ||