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. Author manuscript; available in PMC: 2016 Oct 5.
Published in final edited form as: Inorg Chem. 2015 Sep 23;54(19):9626–9636. doi: 10.1021/acs.inorgchem.5b01722

Figure 5.

Figure 5

MTT cytotoxicity assay of HCT116N (MMR-proficient) and HCT116O (MMR-deficient) cells treated with [Rh(chrysi)(phen)(DPE-Pt(NH3)2Cl)]3+ (left), cisplatin (center), and [Rh(chrysi)(phen)(DPE)]2+ (right). Cells were incubated with each complex at the concentrations indicated for 72h. After the incubation period, cells were treated with the MTT reagent for 4 h, and the resulting formazan crystals were solubilized with acidified SDS. Percent cell viability is defined as the percentage of formazan normalized to that of untreated cells. Standard errors were calculated from 5 replicates.