Table 1.
Clinical details of patients treated with surgical resection of gastroesophageal cancers
Variable | Score | Neo-adjuvant Chemotherapy | No Neo-adjuvant Chemotherapy | P value* |
---|---|---|---|---|
Age | >Median | 9 | 15 | 0.073 |
< Median | 27 | 16 | ||
Histology | Adenocarcinoma | 31 | 24 | 0.180 |
Squamous | 5 | 7 | ||
Stage | I | 11 | 3 | 0.109 |
II | 10 | 12 | ||
III | 15 | 16 | ||
Site | Oesophagus | 30 | 25 | 0.755 |
(includes Siewert Type I and II junctional) | ||||
6 | 6 | |||
Gastric | ||||
(includes Siewert Type III junctional) | ||||
Circumferential Resection Margins | Positive | 6 | 11 | 0.378 |
Negative | 30 | 20 |
There was no significant difference in clinic-pathological characteristics between patients who did and did not receive neo-adjuvant chemotherapy prior to surgery. SPHK1 immunohistochemistry was performed on this cohort as described. *χ2 test. Two-sided p value