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. 2015 Aug 8;4(10):1573–1582. doi: 10.1002/cam4.505

Figure 1.

Figure 1

Expression of miR-139 in lung cancer. (A) Expression of miR-139 in primary NSCLCs (n = 75) and adjacent normal lung tissues (n = 15). The patient characteristics of the 75 primary NSCLCs are described in Table1A. Adjacent normal lung tissues were obtained from randomly selected 15 cases. The experiments were in duplicate and the expression levels are relative to the average expression of the 15 normal lung tissues. The statistical significance of the expression difference was determined using Student's t-test. (B) Association of miR-139 and PDE2A expression in 25 lung cancer cell lines and NHBE. U6 small nuclear RNA and ACTB was used as internal controls. The experiments were in triplicate and the list of cell lines is shown in Table S2. A Pearson's correlation coefficient was calculated between miR-139 and PDE2A expression. (C) Association of miR-139 and PDE2A expression in primary NSCLCs and adjacent normal lung tissues. U6 small nuclear RNA and ACTB was used as internal controls. A Pearson's correlation coefficient was calculated between miR-139 and PDE2A expression. NSCLCs, non-small-cell lung cancer; NHBE, normal human bronchial epithelial cells.