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Effect of EZH2 knockdown on miR-139 and PDE2A expression. (A and B) Expression of EZH2 after EZH2 knockdown with and without Tricostatin A (TSA) (0.1 µmol/L for NCI-H2170 and 0.5 µmol/L for ABC-1). The data are shown as mean ± SD (n = 3). (C and D) Expression of miR-139 after EZH2 knockdown with and without TSA. The data are shown as mean ± SD (n = 3). (E and F) Expression of PDE2A after EZH2 knockdown with and without TSA. The data are shown as mean ± SD (n = 3).
