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. 2015 Jul 31;1(6):e1500251. doi: 10.1126/sciadv.1500251

Fig. 3. vmPFC-amygdala circuit silencing impairs extinction formation and BL recruitment.

Fig. 3

(A and B) Green light shone on ArchT-AAV–expressing vmPFC axons in the amygdala during extinction training (A) increased freezing during training or subsequent (light-free) retrieval (B). (C and D) Light shone during retrieval (after light-free extinction training) (C) did not alter freezing (D). (E to G) Green light shone during extinction training (E) decreased the number of Zif268+ cells in the LA (F) and BL (G) (example images shown on the right; scale bar, 50 μm). For virus expression and optical fiber locations, see Fig. 1, C, J, and K. Extinction trial-block = 5 CS presentations.