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. Author manuscript; available in PMC: 2015 Oct 24.
Published in final edited form as: Cancer Prev Res (Phila). 2012 Feb 7;5(4):603–611. doi: 10.1158/1940-6207.CAPR-11-0538

Figure 5.

Figure 5

Diurnal fluctuation in conversion of oral GR and SF from broccoli sprout extracts to urinary DTC. There were 3 cohorts (A, B, and C) each comprising 3 male subjects. All subjects were dosed at 8-h intervals (7 AM, 3 PM, and 11 PM) and complete urines were collected during the ensuing 8-h periods for 7 days (20 doses and 21 urine collections). The doses (and ages) were as follows: Cohort A (28, 45 and 46 y old), 25 μmol of SF; Cohort B (45, 46, and 57 y old), 25 μmol of GR; Cohort C (45, 45, and 48 y old), 100 μmol of GR. Mean excretion per time period (morning, afternoon, and nighttime) for all 3 subjects who received SF-rich BSE are plotted in 5D, and mean excretion per time period for the 6 subjects who received GR-rich BSE are shown in 5E. Percent conversion of dose values are normalized to 100% for the morning time period for both 5D and 5E.