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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Cancer Prev Res (Phila). 2015 Feb 5;8(5):410–418. doi: 10.1158/1940-6207.CAPR-14-0329

Figure 2.

Figure 2

Partial correlation network displaying conditionally independent relationships between O-PLS-DA selected discriminants for adenocarcinoma (Table 2). Edge color and width denote the direction and magnitude of partial correlations (pFDR≤0.05). Node color displays the direction of the change in tumor relative to non-malignant tissue (green, decrease; red, increase; pFDR ≤ 0.05). Node size displays the metabolite loading (empirical importance) in the O-PLS-DA model and shape denotes the biochemical super class of each molecule. See metabolite O-PLS-DA model loading in Table S4 for quantitative differences in metabolites and corresponding node sizes. Node inset boxplots summarize differences in z-scaled measurements between tumor and non-malignant tissue.